N6-METHYLADENOSINE MODIFICATION OF HIV-1 RNA SUPPRESSES TYPE-I INTERFERON INDUCTION IN DIFFERENTIATED MONOCYTIC CELLS AND PRIMARY MACROPHAGES.

N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages.

N6-methyladenosine (m6A) is a prevalent RNA modification that plays a key role in regulating eukaryotic cellular mRNA functions.RNA m6A modification is regulated by two groups of cellular proteins, writers and erasers that add or remove m6A, respectively.HIV-1 RNA contains m6A modifications that modulate viral infection and gene expression in CD4+

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Review of core technologies for development of 2G HTS NMR/MRI magnet: A status report of progress in Korea University

In this paper, we briefly review our recent progress on Toner Originals development of core technologies for 2G HTS NMR/MRI magnets at Korea University.To outperform the current state-of-art NMR/MRI magnet systems, we have developed the following technologies: 1) a REBCO-REBCO superconducting joint for operation of persistent current mode; 2) parti

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Post-craniotomy Pain: An Update

Approximately two-thirds of patients experience moderate to severe intensity pain following craniotomy.It Insoles is often undertreated due to fear of unfavorable side effects of commonly used analgesic drugs.The objectives of this review are to discuss the various aspects of acute and chronic post-craniotomy pain including its incidence, pathophys

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Why Do Green Parties Emerge?

The emergence of Green parties has long been explained by the development of post-materialist values in advanced democracies.This article takes a somewhat different perspective, by reassessing the importance of institutional and strategic variables.The comparison between the British and the German cases reinforces the notion that post-materialist v

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